芳香族氨基酸对羟基磷灰石晶体的生长、颜色和荧光特性的影响

Effects of Aromatic Amino Acids on Growth,Fluorescence,and Color Properties of Hydroxyapatite

目的:研究3种芳香族氨基酸(AAA)对羟基磷灰石(HA)晶体的生长、颜色和荧光特性的影响,为牙科颜色材料开发提供思路。方法:采用水热法合成HA和AAA复合物(HA-AAA)作为实验组,并行X-线晶体衍射(XRD)、傅立叶红外光谱(FTIR)、紫外分光光度计(UV)、颜色、拉曼(Raman)和激光龋齿检测仪(DIAGNOdent)检测。同法合成纯HA样本作对照组。计算样本的结晶度指数(CI)、相对碳酸盐含量(RCC)、白度值W*、拉曼相对位移(RRI)、激光诱导荧光强度(FI)、半高全宽(FWHM)和激光龋齿检测仪读数DD值,分析HA-AAA的指数与对照组是否有统计学差异。结果:HA-AAA的CI、RRC值明显低于实验组,W*、FI和DD值与对照组有统计学差异。结论:AAA对HA晶体生长产生抑制作用,并明显加深HA颜色且增强激光诱导荧光。

Objective:To study the effects of three aromatic amino acids(AAA)on the growth,color,and fluorescence characteristics of hydroxyapatite(HA)crystals,and to provide ideas for the development of dental color materials.Methods:The hydrothermal method was used to synthesize HA and AAA complex(HA-AAA)as test group.X-ray diffraction(XRD),Fourier infrared spectroscopy(FTIR),ultraviolet spectrophotometer(UV),color,Raman,and DIAGNOdent were used to detect the sample.Pure HA samples were synthesized in the same way as control group.The crystallinity index(CI),relative carbonate content(RCC),whiteness value W,Raman relative intensity(RRI),laser-induced fluorescence intensity(FI),full height at half maximum(FWHM),and DD value of DIAGNOdent were calculated and analyzed.Results:The CI and RRC values of HA-AAA were significantly lower than those of the test group,and the W,FI,and DD values were statistically different from those of the control group.Conclusion:AAA can inhibit the growth of HA crystals,and significantly deepen the HA color and enhance the laser-induced fluorescence.