灵芝多糖和猪苓多糖及其复方的免疫调节作用研究进展

Advances in Immunoregulation Effects of Ganoderma lucidum Polysaccharide and/or Polyporus umbellatus Polysaccharide

多糖是由多个单糖聚合而成的一类天然高分子物质,食用菌多糖是多糖家族中的一员,作为天然化合物,食用菌多糖在食品、药品和保健品研发中具有良好的发展前景。灵芝和猪苓均是珍贵的食药用菌,有很高的营养价值。两者均有广泛的药理作用,如抗肿瘤、免疫调节、抗氧化等。灵芝和猪苓中含有多种活性成分,其中,多糖主要发挥免疫调节的作用,能够作用于多种免疫细胞,调节机体的免疫功能。据报道,灵芝多糖和猪苓多糖组成的复合制剂能增强小鼠先天性免疫功能。本文将对多糖的性质进行简要介绍,总结概括灵芝多糖和猪苓多糖的免疫调节功能及作用机制,为灵芝多糖和猪苓多糖在免疫功能调节方面的研发和应用提供指导。

Polysaccharide is a kind of natural macromolecule that is polymerized from many monosaccharide molecules.Edible mushroom polysaccharide is a member of the polysaccharide family.As a natural compound,edible mushroom polysaccharide shows great promise in the research and development of foods,medicine and health care products.Ganoderma lucidum and Polyporus umbellatus are valuable edible and medicinal mushrooms,which have great flavor and high nutritional value.Both of them have a wide range of pharmacological effects,such as anti-tumor,immunoregulation,and antioxidant effect.Ganoderma lucidum and Polyporus umbellatus contain many bioactive ingredients,separately.Among them,polysaccharides play an important role in immune regulation by acting on a variety of immune cells,thereby regulating the immune function of the body.Modern pharmacological studies have found that a combination of Ganoderma lucidum polysaccharide and Polyporus umbellatus polysaccharide is able to enhance the immune function of mice.In this paper,we will briefly describe the characteristics of polysaccharides,and summarize the immunoregulatory functions and mechanisms of Ganoderma lucidum polysaccharide and Polyporus umbellatus polysaccharide in order to guide future studies in this area.