焦虑、抑郁在体外受精—胚胎移植女性患者自我效能感与生育生活质量间的中介效应研究

Study on the mediating effect of anxiety,depression between self-efficacy and life quality of reproduction in female patients undergoing in vitro fertilization-embryo transfer

目的探讨焦虑、抑郁在体外受精—胚胎移植(IVF-ET)女性患者自我效能感与生育生活质量间的中介效应,为不孕症患者的心理干预提供理论依据。方法采用方便取样的方法,选取2018年1月~10月就诊于东部战区总医院生殖医学中心的200例IVF-ET女性患者,应用一般资料调查表、焦虑量表(SAS)、抑郁量表(SDS)、不孕症自我效能感量表(ISE)及生育生活质量量表(FertiQoL)进行问卷调查。使用SPSS21.0和AMOS21.0对调查数据进行统计学分析。结果本研究共发放问卷200份,有效回收190份。焦虑抑郁、自我效能感及生育生活质量存在不同程度的相关性,焦虑抑郁水平与自我效能感呈负相关、与生育生活质量呈负相关(P<0.05)。焦虑抑郁作为中介变量,使自我效能感对生育生活质量的预测效应从0.65降低为0.26.结构方程模型验证分析结果为焦虑抑郁作为中介变量使自我效能感对生育生活质量的影响从0.49降低为0.20。结论焦虑抑郁是自我效能感与生育生活质量的中介变量,降低IVF-ET女性患者的焦虑抑郁水平、提高心理健康水平有助于提高患者的自我效能感水平,改善患者生育生活质量。

Objective To explore the mediating effect of anxiety,depression between self-efficacy and life quality of reproduction in female patients undergoing in vitro fertilization-embryo transfer(IVF-ET),provide a theoretical basis for psychological intervention of infertile patients.Methods Convenience sampling method was used to select 200 female patients undergoing IVF-ET in Center of Reproductive Medicine,General Hospital of Eastern Theater Command from January to October in 2018.General information questionnaire,Self-rating Anxiety Scale(SAS),Self-rating Depression Scale(SDS),Infertility Self-efficacy Scale(ISE),and the Fertility Quality of Life(FertiQoL)were used for questionnaire survey.SPSS21.0 software and AMOS21.0 software were used for statistical analysis.Results A total of 200 questionnaires were distributed,and 190 valid questionnaires were retrieved.Anxiety,depression were correlated with self-efficacy,life quality of reproduction in varying degrees.Anxiety and depression levels were negatively correlated with self-efficacy and life quality of reproduction(P<0.05).As the mediating variables,anxiety and depression reduced the predictive effect of self-efficacy on life quality of reproduction from 0.65 to 0.26.Structural equation model showed that as the mediating variables,anxiety and depression reduced the predictive effect of self-efficacy on life quality of reproduction from 0.49 to 0.20.Conclusion Anxiety and depression are the mediating variables of self-efficacy and life quality of reproduction,which can reduce anxiety and depression levels of female patients undergoing IVF-ET,increase the levels of psychological health and self-efficacy,improve life quality of reproduction.