食管支架在复杂性食管狭窄中的研究进展

Research progress in esophageal stent implantation for complex esophageal stricture

食管狭窄为常见的消化类疾病,其中复杂性食管狭窄的患病比例逐年上升。支架置入术作为有效治疗手段已经成功应用于多数食管狭窄,但置入后不良反应限制了食管支架在治疗复杂性食管狭窄中的应用和推广。随着新技术及治疗方案日益进步,用于复杂性食管狭窄的食管支架成为新的研究方向,其中以高聚物线材为主体的生物可降解支架因其优异的组织相容性及可降解性有希望成为解决复杂性食管疾病的有效途径。文章从复杂性食管狭窄治疗现状、食管支架的临床使用情况以及新型技术的应用前景作介绍,以期为用于治疗复杂性食管狭窄的新型食管狭窄治疗方案提供研究依据和方向。

Esophageal stricture is a common digestive disease,among which the proportion of complex esophageal stricture is increasing year by year.Being an effective treatment,stent implantation has been successfully employed in most cases with esophageal stricture.Unfortunately,post-stenting adverse reactions have limited the development of esophageal stent implantation in the treatment of complex esophageal strictures.Along with the increasing progress of new technologies and therapeutic schemes,the research on the esophageal stents specially used for complex esophageal strictures has become a hot topic.Being its excellent histocompatibility and degradability,the biodegradable stent using polymer wires as the main materials is a hopeful device that will solve the problem in treating complex esophageal strictures.This article aims to make a comprehensive review concerning the present situation of the treatment of complex esophageal stricture,the clinical utilization of esophageal stents and the application prospect of new techniques in order to provide the basis and direction of the further studies on the new therapeutic schemes for complex esophageal strictures.