期刊文献+

CSF Brain-Reactive Autoantibodies are Elevated in Patients with Viral Encephalitis 被引量:3

原文传递
导出
摘要 Dear Editor,Brain-reactive autoantibodies are thought to play an important role in mediating disorders of the central nervous system(CNS).These antibodies direct the processes underlying several diseases,such as multiple sclerosis(MS),neuromyelitis optica(NMO),and neuropsychiatric systemic lupus erythematosus[1-3].In infectious diseases of the CNS,the pathogen itself is regarded to play a major role in the pathogenesis[4].
出处 《Neuroscience Bulletin》 SCIE CAS CSCD 2020年第8期942-946,共5页 神经科学通报(英文版)
基金 supported by the National Natural Science Foundation of China(81600936 and 81701046) the Natural Science Foundation of Chongqing Municipality,China(cstc2018jcyJAX0511)。
  • 相关文献

参考文献3

二级参考文献47

  • 1Ando DG, Clayton J, Kono D, Urban JL, Sercarz EE. Encephalitogenic T cells in the B10.PL model of experimental allergic encephalomyelitis (EAE) are of the Th-1 lymphokine subtype. Cell Immunol 1989, 124: 132-143.
  • 2Huseby ES, Liggitt D, Brabb T, Schnabel B, Ohlen C, Goverman J. A pathogenic role for myelin-specific CD8(+) T cells in a model for multiple sclerosis. J Exp Med 2001, 194: 669-676.
  • 3Crawford ME Yan SX, Ortega SB, Mehta RS, Hewitt RE, Price DA,et al. High prevalence of autoreactive, neuroantigen-specific CDS+ T cells in multiple sclerosis revealed by novel flow cytometric assay. Blood 2004, 103: 4222-4231.
  • 4Link H. The cytokine storm in multiple sclerosis. Mult Scler 1998, 4: 12-15.
  • 5Trinchieri G, Pflanz S, Kastelein RA. The IL-12 family of heterodimeric cytokines: new players in the regulation of T cell responses. Immunity 2003, 19: 641-644.
  • 6Xiao BG, Ma CG, Xu LY, Link H, Lu CZ. IL-12/IFN-γ/NO axis plays critical role in development of Th1-mediated experimental autoimmune encephalomyelitis. Mol Immunol 2008, 45: 1191-1196.
  • 7Hedegaard C J, Krakauer M, Bendtzen K, Lund H, Sellebjerg F, Nielsen CH. T helper cell type 1 (Th1), Th2 and Th17 responses to myelin basic protein and disease activity in multiple sclerosis. Immunology 2008, 125: 161-169.
  • 8Frohman EM, Filippi M, Stuve O, Waxman SG, Corboy J, Phillips JT, et al. Characterizing the mechanisms of progression in multiple sclerosis: evidence and new hypotheses for future directions. Arch Neurol 2005. 62: 1345-1356.
  • 9Falcone M, Rajan AJ, Bloom BR, Brosnan CE A critical role for IL-4 in regulating disease severity in experimental allergic encephalomyelitis as demonstrated in IL-4-deficient C57BL/6 mice and BALB/c mice. J Immunol 1998. 160: 4822-4830.
  • 10Bettelli E, Das MP, Howard ED, Weiner HL, Sobel RA, Kuchroo VK. IL-10 is critical in the regulation of autoimmune encephalomyelitis as demonstrated by studies of IL-10 and IL-4 deficient and transgenic mice. J Immunol 1998, 161: 3299-3306.

共引文献18

同被引文献44

引证文献3

二级引证文献10

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部