创伤后应激障碍对新型冠状病毒肺炎患者神经软体征的影响

Effects of post-traumatic stress disorder on neurological soft signs in patients with COVID-19

目的探讨创伤后应激障碍(PTSD)对新型冠状病毒肺炎(COVID-19)患者神经系统软体征的影响。方法采取整群抽样方法,对82例COVID-19确诊患者进行一般情况量表、创伤后应激障碍自评量表平民版(PCL-C)、神经系统软体征(NSS)评定。结果COVID-19患者PTSD发病率为36.59%,首发严重程度及亲属是否因患COVID-19去世的患者中PTSD的发生率比较差异有统计学意义(P<0.01)。有PTSD患者NSS总分及额叶、颞叶、枕叶高于无PTSD患者(P<0.05)。PCL-C各维度评分与NSS测定总分及额叶软体征评分均呈正相关(P<0.05);创伤性再体验与颞叶软体征评分呈正相关(P<0.05);麻木性回避与顶叶软体征评分呈正相关(P<0.05);警觉性增高与颞叶软体征、枕叶软体征评分均呈正相关(P<0.05)。结论新型冠状病毒肺炎患者存在较为严重的心理健康问题。创伤后应激障碍对新型冠状病毒肺炎患者神经软体征有显著影响。

Objective To explore the effects of post-traumatic stress disorder(PTSD)on neurological soft signs in patients with COVID-19.Methods A total of 82 patients with COVID-19 were selected through cluster sampling and assessed with the general information questionnaire,PTSD Cheeklist-Civilan Version(PCL-C)and neurological soft signs(NSS).Results The incidence rate of PTSD in patients with COVID-19 was 36.59%.There existed significant differences in the incidence rates of PTSD among patients with different levels of first-onset severity and among patients whether their relatives were died of COVID-19(P<0.01).The patients with PTSD had higher total score and factor scores of frontal lobe,temporal lobe,occipital lobe of NSS than patients without PTSD(P<0.05).All factor scores of PCL-C were positively correlated with the total score and factor score of frontal lobe of NSS(P<0.05).Traumatic re-experience was positively correlated with the factor score of temporal lobe of NSS(P<0.05).Numb avoidance was positively correlated with the factor score of parietal lobe of NSS(P<0.05).Alertness increase was positively correlated with factor scores of temporal lobe and occipital lobe of NSS(P<0.05).Conclusion Patients with COVID-19 have serious mental health problems,and PTSD has significant impact on NSS in patients with COVID-19.