小剂量阿司匹林联合氯吡格雷治疗缺血性脑血管病的临床效果分析

Clinical Effect Analysis of Low-dose Aspirin Combined with Clopidogrel in the Treatment of Ischemic Cerebrovascular Disease

目的:探讨小剂量阿司匹林联合氯吡格雷治疗缺血性脑血管病的临床疗效。方法:选取2018年7月至2019年8月期间在本院接受治疗的缺血性脑血管病患者80例,随机分为观察组和对照组,两组患者各40例,治疗方式不同。对照组采用常规治疗+氯吡格雷治疗,观察组采用常规治疗+小剂量阿司匹林联合氯吡格雷治疗。对比患者疗效、不良反应以及症状改善用时情况。结果:对比疗效,观察组患者总有效率大幅度高于对照组;对比腹泻、皮疹等不良反应,观察组发生率更低;对比患者退热、出院、咳嗽等症状缓解时间,观察组用时较少,优于对照组。结论:对缺血性脑血管病患者采用小剂量阿司匹林联合氯吡格雷进行治疗,其治疗效果良好,安全性较高,产生不良反应较少,患者生活质量改善明显。

Objective:To investigate the clinical efficacy of low-dose aspirin combined with clopidogrel in the treatment of ischemic cerebrovascular disease.Methods:80 patients with ischemic cerebrovascular disease in our hospital from July 2018 to August 2019 were selected and randomly divided into observation group and control group,40 cases in each group.The control group was treated with routine therapy combined with clopidogrel,and the observation group was treated with routine treatment combined with low-dose aspirin and with clopidogrel.Then,the clinical effect,adverse reactions and symptom improvement time were compared.Results:Compared with the curative effect,the total effective rate of the observation group was significantly higher than that of the control group;the incidence of diarrhea,rash and other adverse reactions in the observation group was lower;the remission time of fever,discharge,cough and other symptoms of the observation group was less than that of the control group.Conclusion:Low dose aspirin combined with clopidogrel is effective in the treatment of ischemic cerebrovascular disease.The drug was safety,less adverse reactions and obvious improvement of patients’ quality of life.