经直肠超声联合血清PSA在经会阴前列腺穿刺活检诊断前列腺癌中的价值

Values of transrectal ultrasonography combined with serum PSA and perineal prostate biopsy in the diagnosis of prostate cancer

目的:探讨经直肠超声(Tranrectal ultrasound,TRUS)检查联合血清前列腺特异性抗原(Prostate specific antigen,PSA)在经会阴前列腺穿刺活检诊断前列腺癌(Prostate cancer,PCA)中的临床意义。方法:对我院2016年6月至2018年11月收治的203例疑诊前列腺癌患者,回顾分析经直肠超声检查图像特征和经会阴前列腺穿刺活检结果与血清PSA间的关系。结果:203例血清PSA增高的患者中,检出前列腺癌患者110例,检出率为54.19%。超声图像特征越明显,前列腺癌穿刺活检的检出率越高(P<0.05)。随着血清PSA值增高以及年龄的增长,前列腺癌穿刺活检的检出率增高(P<0.05)。术后出现肉眼血尿19例(9.35%),发热3例(1.48%),迷走神经反射1例(0.05%),尚未出现严重并发症的患者。结论:经直肠超声联合血清PSA水平行直肠超声引导下前列腺穿刺活检,对临床诊断早期前列腺癌具有重要的参考价值。

Objective:To investigate the clinical significance of transrectal ultrasonography(TRUS)combined with serum prostate specific antigen(PSA)in the diagnosis of prostate cancer.Methods:Two hundred and three patients with suspected prostate cancer admitted to our hospital from June 2016 to November 2018 were retrospectively analyzed for the characteristics of transrectal ultrasonography and the relationship between the results of perineal prostate biopsy and serum PSA.Results:Among 203 patients with elevated prostate serum PSA,110 patients were detected with prostate cancer,with a detection rate of 54.19%.The more obvious the characteristics of ultrasound images,the higher the detection rate of prostate cancer biopsy(P<0.05).With the increase of serum PSA value and age,the detection rate of prostate cancer biopsy increased(P<0.05).There were 19 cases(9.35%)of hematuria,3 cases(1.48%)of fever and 1 case(0.05%)of vagus nerve reflex after surgery,and no serious complications of the patients.Conclusion:Transrectal ultrasonography combined with serum PSA level for prostate biopsy guided by rectal ultrasonography has important reference value for clinical diagnosis of early prostate cancer.