线粒体非典型功能障碍与神经系统疾病相关研究进展

The new research on the relationship between mitochondrial atypical dysfunction and neurological diseases

线粒体非典型功能包括调节细胞凋亡、产生自由基和氧化剂、调控钙离子缓冲等。近年来随着对线粒体病研究与认知的深入,发现除了ATP合成障碍以外,线粒体一些非典型的功能障碍也与神经系统疾病关系密切。本文将对线粒体非典型功能障碍与神经系统疾病相关研究进展做一综述。

The atypical functions of mitochondria include regulation of apoptosis,generation of free radicals and oxidants,regulation of calcium buffering and so on.In recent years,with the deepening of research and in-depth understanding of mitochondrial diseases,it has been found that in addition to ATP synthesis disorders,some atypical dysfunctions of mitochondria are also related to neurological diseases closely.This article reviews a new research progress about the relationship between mitochondrial atypical dysfunction and neurological diseases.