盐酸利托君联合黄体酮治疗孕妇先兆早产的疗效及对新生儿结局的影响

Effect of Ritodrine Hydrochloride Combined with Progesterone in the Treatment of Threatened Premature Delivery and its Influence on Neonatal Outcome

目的:分析对先兆早产孕妇进行盐酸利托君联合黄体酮治疗的疗效及对新生儿结局的影响。方法:选择2018年1月—2020年2月,收治的60例先兆早产孕妇作为研究对象,并分为观察组(30例,接受盐酸利托君联合黄体酮治疗方式)和对照组(30例,接受盐酸利托君治疗方式)。结果:对比两组孕妇治疗情况、新生儿结局,与对照组相对比,观察组孕妇治疗情况更好,新生儿结局更佳,差异均有统计学意义(P<0.05)。结论:对先兆早产孕妇实施盐酸利托君联合黄体酮治疗方式,不仅能有效抑制孕妇的宫缩状态,还能促进胎肺成熟,使胎儿处于较安全的生长环境,有效延长妊娠周期,改善新生儿结局,提升新生儿生存概率。

Objective:To analyze the clinical effect of ritodrine hydrochloride combined with progesterone in treatment of threatened premature delivery and its influence on neonatal outcomes.Methods:60 cases of pregnant women with threatened preterm birth and who treated from January 2018 to February 2020 were selected as the research objects,and the patients were divided into observation group(30 cases,received ritodrine hydrochloride combined with progesterone treatment)and control group(30 cases,received ritodrine hydrochloride treatment).Results:The treatment and neonatal outcomes of two groups were compared,the treatment of pregnant women in the observation group was better than that in the control group,and the neonatal outcome was better,and the differences were statistically significant(P<0.05).Conclusion:The application of ritodrine hydrochloride combined with progesterone in treatment of threatened premature delivery which can not only effectively inhibit the uterine contraction of pregnant women,but also promote the fetal lung maturity,so that the fetus can be in a safer growth environment,effectively prolong the pregnancy cycle,improve the neonatal outcomes,and enhance the survival rate of newborns.