左旋多巴联合普拉克索治疗原发性帕金森病的临床分析

The clinical effect of simvastatin combined with Madopar in elderly patients with Parkinson's disease and atherosclerosis

目的:对左旋多巴联合普拉克索治疗原发性帕金森病的临床疗效进行分析。方法:选取接受治疗的原发性帕金森病患者50例作为研究对象,经简单随机分组将其分为两组,对照组给予左旋多巴治疗,观察组采用左旋多巴联合普拉克索治疗,对比两组患者的汉密尔顿抑郁评分、帕金森统一评分量表评分。结果:观察组患者的HAMD评分与UPDRS各项评分均优于对照组,差异有统计学意义(P<0.05)。结论:为原发性帕金森病患者实施左旋多巴联合普拉克索治疗的临床疗效确切。

Objective To study the clinical effect of simvastatin combined with Madopar in elderly patients with Parkinson's disease and atherosclerosis.Method 50 elderly patients with Parkinson's disease and atherosclerosis who were treated in our hospital were randomly divided into two groups,Madopa treatment(control group)and simvastatin combined with Madopa treatment(observation group).The clinical total effective rate,Webster score,UPDRS score and the incidence of adverse reactions were compared between the two groups.Results The total effective rate,Webster score,UPDRS score and adverse reaction rate of the elderly patients with Parkinson's disease and atherosclerosis in the observation group were better than those in the control group(P<0.05).Conclusion The combination of Madopar and simvastatin is safe and effective in the treatment of elderly patients with Parkinson's disease and atherosclerosis.