慢性肾功能不全合并脑出血预后相关因素分析

Analysis of Prognostic Factors of Chronic Renal Insufficiency with Cerebral Hemorrhage

目的:探讨慢性肾功能不全合并脑出血的预后相关因素。方法:回顾性分析笔者所在医院2014-2019年诊断为慢性肾功能不全合并脑出血38例患者,统计预后良好组和预后不良组发病到入院时间、年龄、入院时肌酐值、尿素氮、血钾、血钠、血红蛋白、入院时出血量、是否手术、入院时GCS评分、出院时GOS评分指标。结果:预后良好组和预后不良组入院时肌酐值、尿素氮、血钾、血钠、血红蛋白、是否手术比较,差异无统计学意义(P>0.05)。预后良好组的出血量少于预后不良组(P<0.05),预后良好组GCS评分大于预后不良组(P<0.05)。平均出血量、GCS评分这两个因素的多因素非条件Logistic回归分析差异有统计学意义(P<0.05)。结论:影响慢性肾功能不全合并脑出血的预后因素主要为入院时出血量、GCS评分。

Objective:To explore the prognostic factors of chronic renal insufficiency with cerebral hemorrhage.Method:A total of 38 patients with chronic renal insufficiency and cerebral hemorrhage who diagnosed in our hospital from 2014 to 2019 were analyzed retrospectively.The time from onset to admission,age,creatinine value at admission,urea nitrogen,blood potassium,blood sodium,hemoglobin,amount of bleeding at admission,operation or not,GCS score at admission and GOS score at discharge in the group with good prognosis and the group with poor prognosis were counted.Result:There was no significant difference in creatinine,urea nitrogen,blood potassium,blood sodium,hemoglobin and operation between the patients in the group with good prognosis and the group with poor prognosis(P>0.05).The amount of bleeding in the group with good prognosis was less than that in the group with poor prognosis(P<0.05),and the GCS score in the group with good prognosis was higher than that in the group with poor prognosis(P<0.05).The multivariate non-conditional Logistic regression analysis of the two factors of average blood loss and GCS score were significantly different(P<0.05).Conclusion:The main prognostic factors of chronic renal insufficiency combined with cerebral hemorrhage are the amount of bleeding on admission and GCS score.