注射A型肉毒毒素治疗眼睑肌张力障碍临床研究

Clinical Study of Type A Botulinum Toxin in Treatment of Eyelid Dystonia

目的:探究眼睑肌张力障碍注射A型肉毒毒素治疗的临床效果。方法:随机抽取笔者所在医院2017年11月-2020年3月收入的眼睑肌张力障碍患者总计80例,按照随机数字表法分为两组,对照组40例采取常规治疗,观察组40例在对照组基础上联合注射A型肉毒毒素治疗,比较两组干预效果。结果:观察组治疗总有效率为97.50%,高于对照组的85.00%,差异有统计学意义(P<0.05);观察组并发症发生率为10.00%,对照组为7.50%,两组差异无统计学意义(P>0.05)。结论:眼睑肌张力障碍患者采取注射A型肉毒毒素治疗,整体疗效显著,且用药期间并发症发生率偏低,值得应用。

Objective:To study the clinical effect of type A Botulinum Toxin in treatment of eyelid dystonia.Method:A total of 80 patients with eyelid dystonia from November 2017 to March 2020 who treated in our hospital were chosen and grouped by random number table,40 cases in each group.The control group took the routine treatment,on the basis of the former,the observation group took Type A Botulinum Toxin Injection.The intervention effects were compared.Result:The total effective rate in the observation group(97.50%)was higher than that in the control group(85.00%),the difference was statistically significant(P<0.05).The complication rate was 10.00%in the observation group and 7.50%in the control group,there was no statistically significant difference(P>0.05).Conclusion:Type A Botulinum Toxin Injection has obvious overall effects and few complications in clinical use.