盐酸替罗非班在急性ST段抬高型心肌梗死治疗的临床应用

Clinical Application of Tirofiban Hydrochloride in the Treatment of Acute ST Segment Elevation Myocardial Infarction

目的:探究盐酸替罗非班在急性ST段抬高型心肌梗死治疗中的临床效果。方法:选取2018年3月-2019年8月笔者所在科室86例急性ST段抬高型心肌梗死患者作为研究对象,选用电脑随机数字方式分为对比组(43例)和研究组(43例),对比组进行氯化钠治疗,研究组进行盐酸替罗非班治疗,分析两组术后血流灌注状况、术后1个月心功能指标及术后不良事件发生率。结果:研究组TIMI分级优于对比组;LVSED、LVEDD小于对比组,LVEF大于对比组,术后发生不良事件发生率低于对比组,差异有统计学意义(P<0.05)。结论:在ST段抬高型心肌梗死患者经皮冠状动脉介入术中采用盐酸替罗非班,能够更好地改善冠脉血流灌注状况,改善患者的心功能,减少术后不良事件的发生,在实际临床中有显著的功效,值得推广运用。

Objective:To explore the clinical effect of Tirofiban Hydrochloride in the treatment of acute ST-elevation myocardial infarction.Method:From March 2018 to August 2019,a total of 86 patients with acute ST-segment elevation myocardial infarction in the author’s department were selected as the research objects.Computer random numbers were used to divide them into the comparison group(43 cases)and the study group(43 cases),the comparison group was treated with Sodium Chloride,the study group was treated with Tirofiban Hydrochloride,and the postoperative blood flow perfusion status,cardiac function indicators and the incidence of postoperative adverse events in the two groups were analyzed.Result:The data showed that the TIMI classification of the study group was better than that of the comparison group;LVSED and LVEDD was smaller than those of the comparison group,LVEF was larger than that of the comparison group,and the incidence of postoperative adverse events was lower than that of the comparison group,and the differences were statistically significant(P<0.05).Conclusion:The use of Tirofiban Hydrochloride in patients with ST-segment elevation myocardial infarction can better improve coronary blood perfusion,improve cardiac function,and reduce the incidence of postoperative adverse events.It has significant effect in actual clinical,it is worth popularizing and using.