摘要
脓毒症严重威胁人类生命健康,目前其发病机制仍不清楚,脓毒症模型的建立有助于人们更好的研究脓毒症。本文就脓毒症动物模型的种类,建模方法,优、缺点,适用范围等进行综述,为日后脓毒症研究中动物模型的选择提供参考。
Sepsis is a serious threat to human life and health,and its pathogenesis is still unclear.The establishment of sepsis models will help researchers study sepsis.This article reviews the types of sepsis animal models and their modeling methods,advantages,disadvantages,scope of application,etc.,so as to provide information for the selection of animal models in sepsis research in the future.
作者
彭凤辉
邓晓彬
吕立文
Peng Fenghui;Deng Xiaobin;LüLiwen(Emergency Department,People’s Hospital of Guangxi Zhuang Autonomous Region,Nanning 530021,China)
出处
《广西医科大学学报》
CAS
2020年第8期1577-F0003,共5页
Journal of Guangxi Medical University
基金
广西壮族自治区人民医院青年基金资助项目(No.QN2018-4)
2019年黎介寿肠道屏障研究基金资助项目(No.Z-2017-24-2009)
广西科技攻关计划资助项目(No.桂科攻15277007)。
关键词
脓毒症
动物模型
内毒素
盲肠结扎穿孔
sepsis
animal model
endotoxin
cecal ligation and perforation