摘要
采用低温冷冻的方法,通过改变聚乙烯醇(PVA)和聚乙烯吡咯烷酮碘络合物(PVP-I)的配比、冷冻时间、冷冻-解冻循环次数,制备出一种可调控力学性能的PVA/PVP-I复合水凝胶.研究了该复合水凝胶的机械性能、微观结构、碘缓释性能和抑菌性质.研究结果表明,PVA/PVP-I复合水凝胶可调控的力学性质可以满足伤口敷料对水凝胶力学性质的需求;复合水凝胶的网络结构可以有效降低碘在紫外线下的分解速度,实现对碘的稳定保护作用及控制释放,从而发挥水凝胶持续抑菌性能,为抑菌水凝胶的设计制备提供了新思路.
A low-temperature freezing method was used to prepare a PVA/PVP-I composite hydrogel with ad⁃justable mechanical properties by changing the ratio of PVA and iodophor(PVP-I),the freezing time,and the number of freeze-thaw cycles.The mechanical properties,microstructure,iodine release and bacteriostatic property of the composite gel were characterized.The results show that the controllable mechanical properties of the PVA/PVP-I composite hydrogel can meet the demand for wound dressing;the network structure of the composite hydrogel can effectively reduce the decomposition rate of iodine under ultraviolet rays,and achieve sustainable release of iodine,thereby exerting antibacterial properties,broadening the scope of application of iodine disinfectants.
作者
宫宇宁
王奇
王红蕾
关爽
GONG Yuning;WANG Qi;WANG Honglei;GUAN Shuang(College of Chemistry and Biology,Changchun University of Technology,Changchun 130021,China)
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
2020年第9期2078-2084,共7页
Chemical Journal of Chinese Universities
基金
吉林省自然科学基金(批准号:20190201078JC)资助.
关键词
聚乙烯醇
碘伏
水凝胶
碘释放
Polyvinyl alcohol
Iodophor
Hydrogel
Iodine release
