硬化性黏液水肿1例

A Case of Scleromyxedema

患者女,43岁,全身泛发性丘疹、硬化伴瘙痒1年半。皮损组织病理示:真皮内黏蛋白沉积,阿辛兰染色阳性;免疫固定电泳:IgG(+),轻链λ(+);骨髓细胞学检查未见明显异常。诊断:硬化性黏液水肿。

A 43-year-old female presented generalized papules,sclerosis and pruritus for one and a half years.Histopathology examination revealed mucin deposition in the dermis,accompanied by positive alcian blue staining.Immunofixation electrophoresis showed positive of immunoglobulin G and λ light chain.There were no obvious abnormalities in bone marrow cytology examination.Therefore,the patient was diagnosed as scleromyxedema.