摘要
目的:探讨甲状腺结节大小超声造影(contrast-enhanced ultrasound,CEUS)与灰阶超声测值差异在甲状腺微小乳头状癌(papillary thyroid microcarcinoma,PTMC)诊断中的价值。方法:回顾并分析346例经手术后病理学检查证实的甲状腺结节患者(414个甲状腺结节,最大径≤10 mm),其中PTMC 313个(PTMC组),良性病变101个(良性组),术前所有结节均行二维灰阶超声及CEUS检查,并分别测量结节的大小,统计分析PTMC组和良性组的灰阶超声与CEUS结节大小测值是否存在差异。结果:CEUS与灰阶超声结节大小测值比较,良性组差异无统计学意义(P>0.05),PTMC组差异有统计学意义(P<0.05);PTMC组结节大小的CEUS测值明显小于灰阶超声测值。结论:对于最大径≤10 mm甲状腺结节,结节大小的CEUS测值小于灰阶超声测值是PTMC的一项特征,利用结节大小的灰阶超声和CEUS测值差异可以进行结节良恶性的鉴别,该项指标的临床诊断价值值得进一步深入研究。
Objective:To investigate the value of the difference between the size of thyroid nodules measured by contrastenhanced ultrasound(CEUS)and gray-scale ultrasound in the diagnosis of papillary thyroid microcarcinoma(PTMC).Methods:Retrospectively analyzed 346 patients with thyroid nodules(414 thyroid nodules,maximum diameter≤10 mm)confirmed by pathological examination after surgery,including 313 PTMC(PTMC group),benign lesions 101(benign group).All nodules were conducted by the two-dimensional gray-scale ultrasound and CEUS examination,and measured the size of the nodule.Statistical analysis was conducted to determine whether there was any difference in the size of nodules measured by gray-scale ultrasound and CEUS between the PTMC group and the benign group.Results:Comparison of the size of nodules measured by contrast-enhanced ultrasound and gray-scale ultrasound,there was no statistical difference in the benign group(P>0.05),and there was statistical difference in the PTMC group(P<0.05);the nodule size measured by contrast-enhanced ultrasound in PTMC group was significantly smaller than that measured by gray-scale ultrasound.Conclusion:For the thyroid nodule with the maximum diameter≤10 mm,it is a characteristic of micropapillary carcinoma that the measured value of the nodule size by contrast-enhanced ultrasound is less than the measured value by gray-scale ultrasound.The difference between the measured value of the nodule size by gray-scale ultrasound and contrast-enhanced ultrasound can be used to identify the benign and malignant nodules.The clinical diagnostic value of this index is worth further study.
作者
李刚
贾超
高峰
张凡
史秋生
吴蓉
杜联芳
邢晋放
LI Gang;JIA Chao;GAO Feng;ZHANG Fan;SHI Qiusheng;WU Rong;DULianfang;XING Jinfang(Department of Medical Ultrasound,Shanghai General Hospital of Nanjing Medical University,Shanghai 200080,China;Department of Ultrasound,Shanghai General Hospital,Shanghai Jiao Tong University,Shanghai 200080,China;Department of Medical Ultrasound,Shanghai Pudong Hospital,Fudan University Pudong Medical Center,Shanghai 201399,China)
出处
《肿瘤影像学》
2020年第4期381-384,共4页
Oncoradiology
基金
复旦大学附属浦东医院(上海市浦东医院)引进人才科研启动项目(YJRCJJ201804)。
关键词
超声造影
甲状腺微小乳头状癌
结节大小
诊断
Contrast-enhanced ultrasound
Papillary thyroid microcarcinoma
Nodule size
Diagnosis