脂肪抑制液体衰减反转恢复序列增强扫描在肺癌软脑膜转移中的诊断价值

The diagnostic value of contrast-enhanced fluid-attenuated inversion recovery fat saturation magnetic resonance imaging in leptomeningeal metastasis of lung cancer

目的:探究脂肪抑制液体衰减反转恢复序列(T2-weighted imaging fluid-attenuated inversion recovery fat saturation,T2WI-FLAIR-FS)增强扫描在肺癌软脑膜转移中的诊断价值。方法:对20例脑脊液(cerebrospinalfluid,CSF)细胞学检查证实为肺癌软脑膜转移的患者进行常规T1加权压脂(T1 weighted imaging fat saturation,T1WI-FS)增强和T2WI-FLAIR-FS增强扫描,对其扫描结果进行回顾性对照分析。结果:3例患者在常规T1WI-FS增强扫描中漏诊,所有入组患者在T2WI-FLAIR-FS增强扫描中表现为软脑膜不同程度的增厚、强化,与CSF检查结果相符,并且T2WI-FLAIR-FS增强扫描显示的病变范围大于T1WI-FS增强(P<0.05)。结论:T2WI-FLAIR-FS增强扫描显示肺癌软脑膜转移明显优于常规T1WI-FS增强扫描,能提高肺癌软脑膜转移的诊断水平,降低漏诊率。

Objective:To investigate the diagnostic value of T2-weighted imaging fluid-attenuated inversion recovery fat saturation(T2 WI-FLAIR-FS)enhanced scanning in lung cancer with leptomeningeal metastasis.Methods:Routine T1 weighted imaging fat saturation(T1 WI-FS)enhancement and T2 WI-FLAIR-FS scanning were performed in 20 patients with confirmed soft meningeal metastasis of lung cancer by cerebrospinal fluid(CSF)cytology,and the scanning results were retrospectively analyzed.Results:3 cases were missed in conventional T1 WI-FS enhanced scan,all cases showed soft meningeal thickening and enhancement in T2 WI-FLAIR-FS enhanced scan,which was consistent with the results of CSF examination,and the lesion range shown in T2 WIFLAIR-FS enhanced scan was larger than T1 WI-FS enhanced scan(P<0.05).Conclusion:T2 WI-FLAIR-FS enhanced scan showed that lung cancer with leptomeningeal metastasis was superior to conventional T1 WI-FS enhanced scan,and could improve the diagnostic level of lung cancer with leptomeningeal metastasis.