美托洛尔联合胺碘酮治疗急性心肌梗死并发快速性心律失常疗效

Metoprolol Combined with Amiodarone in the Treatment of Acute Myocardial Infarction Complicated with Tachyarrhythmia

目的观察胺碘酮联合美托洛尔治疗急性心肌梗死并发快速性心律失常的临床价值。方法选择将该院2018年5月—2019年5月收治的84例急性心肌梗死并发快速性心律失常患者分为两组,每组42例。对照组服用胺碘酮,观察组在上述方案下给予美托洛尔。比较两组心功能指标、总有效率等方面。结果①观察组总有效率95.23%(40/42)明显优于对照组73.70%(30/42),差异有统计学意义(χ~2=15.527,P<0.05);②观察组LVEF、LVEDD、LVESD以及6MWT等指标分别为(55.9±1.9)%、(50.2±1.5)mm、(33.1±1.3)mm、(328.5±12.3)m;对照组分别为(48.3±1.5)%、(60.6±2.2)mm、(39.4±1.4)mm、(230.3±9.4)m;两组比较差异有统计学意义(t=8.634、8.691、7.521、7.841,P<0.05)。结论胺碘酮联合美托洛尔能够有效治疗急性心肌梗死并发快速性心律失常,有利于改善机体的心脏功能,降低了心肌受损程度,且无明显副作用,提高了患者的生活质量,值得推广应用。

Objective To observe the clinical value of amiodarone combined with metoprolol in the treatment of acute myocardial infarction complicated with tachyarrhythmia.Methods 84 patients with acute myocardial infarction complicated with tachyarrhythmia admitted to our hospital from May 2018 to May 2019 were selected and divided into two groups,42 cases in each group.The control group took amiodarone,and the observation group was given metoprolol under the above regimen.Compare the two groups of cardiac function indicators,total effectiveness and other aspects.Results(1)The total effective rate in the observation group was 95.23%(40/42),which was significantly better than that in the control group,73.70%(30/42),the difference was statistically significant(χ~2=15.527,P<0.05);(2)The observation group LVEF,The indexes of LVEDD,LVESD and 6 MWT are(55.9±1.9)%,(50.2±1.5)mm,(33.1±1.3)mm,(328.5±12.3)m;the control group is(48.3±1.5)%,(60.6±2.2)mm,(39.4±1.4)mm,(230.3±9.4)m;the difference between the two groups was statistically significant(t=8.634,8.691,7.521,7.841,P<0.05).Conclusion Amiodarone combined with metoprolol can effectively treat acute myocardial infarction complicated with tachyarrhythmia,which is helpful to improve the heart function of the body,reduce the degree of myocardial damage,and has no obvious side effects,which is worth promotion and application.