不同年龄段对真菌血症流行病学影响及预后分析

To analyze the correlation between the clinical characteristics and prognosis of fungemia in different-age inpatients

回顾2012~2019年真菌血流感染病例共115例,以了解不同年龄段真菌血症流行病学特点。其中白色假丝酵母菌30例、热带假丝酵母菌29例,近平滑假丝酵母菌27例,光滑假丝酵母菌16例,克柔假丝酵母菌4例,其他9例。真菌血症发病率以男性、青年患者为主;ICU、内科发病率与年龄呈正相关,外科、血液科发病率呈负相关。性别、ICU、血液科、糖皮质激素、呼吸窘迫、糖尿病、药物运用等因素组间差异有统计学意义;预后因素中ICU、休克、内科组间差异有统计学意义。故应根据不同年龄段结合不同因素具体分析,以辅助诊断,改善疾病预后。

In order to analyze the correlation between age factors and the epidemiology, this study reviewed 115 fungemia cases in our hospital during the period 2012-2019. There were 30 strains of Candida albicans,29 stains of Candida tropicalis, 27 strains of Candia para psilosis, 16 strains of Candida glabrata, 4 strains of Candida krusei and 9 strains of others. The study found that fungemia frequently happened in male and young patient. The study also found that the percentage of patient in ICU and department of medicine, were positively correlated with age, while surgery and hematology were negatively correlated with age. For gender, ICU, hematology, glucocorticoids, respiratory distress, diabetes and utilization of drugs, the differences among age groups were statistically significant. For ICU, shock and internal medicine, the differences between prognosis groups were statistically significant. Therefore, clinical analysis should be based on different age and different factors to assist diagnosis and improve prognosis.