彩色超声和X线钼靶摄影在乳腺癌诊断中的价值

Diagnostic Value of Color Ultrasonography and Molybdenum Target Mammography in Breast Carcinoma

目的探讨在乳腺癌的诊断过程中使用彩超和X线钼靶摄影联合检查的临床价值。方法对医院收治的疑似乳腺癌的患者展开研究,选取2015年12月—2017年12月132例患者为研究样本,所有患者依次给予彩色超声检查、X线钼靶摄影检查。以病理检查结果为金标准,比较两种检查方式的临床诊断价值。结果在检查结果方面:彩色超声检查显示阳性患者112例(84.85%)、阴性20例(15.15%),X线钼靶摄影检查显示阳性113例(85.61%)、阴性19例(14.39%),联合检查显示阳性116例(87.88%)、阴性16例(12.12%),而金标准检查显示阳性119例(90.15%)、阴性13例(9.85%),四种检查方式经比较,χ^2=2.026、P=0.567,差异不具备统计学意义。在诊断效能方面:彩色超声检查的特异性、灵敏性、阳性预测值和阴性预测值分别是23.08%、85.71%、91.07%和15.00%,X线钼靶摄影检查依次为30.77%、87.39%、92.04%和21.05%,两者单独检查的诊断效能之间差异不具备统计学意义(P>0.05);但分别与联合检查的特异性92.31%、灵敏性96.64%、阳性预测值99.14%和阴性预测值75.00%相比,差异均具有统计学意义(P<0.05)。结论在乳腺癌的临床诊断中单纯使用超声检查或X线钼靶摄影检查均存在一定的劣势,只有联合使用两种检查方式,才能充分发挥各自的诊断优势,提高临床诊断的正确性,联合应用效果显著。

Objective To discuss the clinical value of colorultrasonography and molybdenum target mammography on diagnosis of breast carcinoma. Methods 132 suspected breast carcinoma patients(December 2015 to December 2017) were chosen. The color ultrasonography and molybdenum target mammography were performed. According to pathological examination results, the clinical diagnostic value based on two examinations was analyzed. Results Color ultrasonography indicated 112 positive cases(84.85%) and 20 negative cases(15.15%);molybdenum target mammography indicated 113 positive cases(85.61%) and 19 negative cases(14.39%);combined examinations indicated 116 positive cases(87.88%) and 16 negative cases(12.12%);gold standard indicated 119 positive cases(90.15%) and 13 negative cases(9.85%);the differences were not statistically significant(χ^2=2.026, P=0.567);diagnosis specificity, sensitivity, positive predictive value and negative predictive value based on color ultrasonography was 23.08%, 85.71%, 91.07% and 15.00%;related value based on molybdenum target mammography was 30.77%, 7.39%, 92.04% and 21.05%;the differences were not statistically significant(P > 0.05);diagnosis specificity, sensitivity, positive predictive value and negative predictive value based on combined examination was 92.31%,96.64%, 99.14% and 75.00%(P < 0.05). Conclusion The single examination of color ultrasonography or molybdenum target mammography has its disadvantages. Therefore, the combined examination can give full play to improvements of diagnosis accuracy.