盐酸氨溴索治疗老年慢性阻塞性肺疾病合并肺感染的效果

Effect of Ambroxol Hydrochloride in the Treatment of Senile COPD With Pulmonary Infection

目的研究盐酸氨溴索治疗老年慢性阻塞性肺疾病(慢阻肺)合并肺感染的效果。方法选择2017年9月—2019年9月期间医院治疗的86例老年慢阻肺合并肺感染患者分为两组,分别采取常规方式治疗(对比组,43例)和给予盐酸氨溴索治疗(研究组,43例),比较两组总有效率、CPIS、APACHEⅡ评分、不良反应。结果研究组临床总有效率97.67%(42/43),高于对比组的81.40%(35/43),差异具有统计学意义,P<0.05;研究组不良反应发生率9.30%(4/43),高于对比组的6.98%(3/43),差异不具有统计学意义,P>0.05;治疗前,对比组、研究组CPIS、APACHEⅡ评分差异不具有统计学意义,P>0.05,治疗后,对比组、研究组CPIS、APACHEⅡ评分均有所降低,但是研究组降低幅度更加明显,且差异具有统计学意义,P<0.05。结论给予老年慢阻肺合并肺部感染患者盐酸氨溴索治疗,有助于提高治疗有效率,改善感染程度和健康状况,安全性可靠。

Objective To study the effect of ambroxol hydrochloride in the treatment of senile COPD with pulmonary infection.Methods 86 elderly patients with chronic obstructive pulmonary disease(COPD)and pulmonary infection treated in our hospital from September 2017 to September 2019 were divided into two groups They were treated with routine methods(control group,43 cases)and ambroxol hydrochloride(study group,43 cases).The total effective rate,CPIs,APACHEⅡscore and adverse reactions were compared between the two groups.Results the total clinical effective rate of the study group was 97.67%(42/43),which was higher than 81.40%(35/43)of the control group,with significant difference P ApacheⅡand ApacheⅡscores were all decreased,but the reduction of the study group was more significant,and the difference was significant(P<0.05).Conclusion Ambroxol hydrochloride is helpful to improve the efficiency of treatment,the degree of infection and health status,and it is safe and reliable.