不同途径应用替罗非班对急诊PCI患者的影响

Effect of Tirofiban in Different Ways on Emergency PCI Patients

目的比较不同途径应用替罗非班对急诊经皮冠状动脉介入手术(percutaneous coronary intervention,PCI)患者的影响。方法于2018年1月—2019年6月,选择医院接受急诊PCI治疗的80例急性心肌梗死患者,随机分为每组40例,对照组静脉注射替罗非班,观察组冠状动脉内注射替罗非班,比较临床疗效、血流分级情况。结果临床总有效率观察组97.50%,高于对照组85.00%(P<0.05)。治疗后,两组的TIMI 3级血流比例与治疗前相比增高,而观察组的TIMI 3级血流比例与对照组相比更高,差异均具有统计学意义,P<0.05。结论冠状动脉内注射替罗非班对急性心肌梗死PCI患者的疗效优于静脉注射替罗非班,可更加有效地促使冠脉复流。

Objective To study the effects of tirofiban on patients undergoing emergency percutaneous coronary intervention(PCI).Methods From January 2018 to June 2019,80 patients with acute myocardial infarction who were treated by PCI in our hospital were selected and randomly divided into 40 cases in each group.In the control group,tirofiban was injected intravenously;in the observation group,tirofiban was injected intravenously.The clinical efficacy and blood flow classification were compared Results The total clinical effective rate in the observation group was 97.50%,which was higher than the control group by 85.00%(P<0.05).After treatment,the ratio of TIMI-3 blood flow in the two groups was higher than that before treatment,while the ratio of TIMI-3 blood flow in the observation group was higher than that in the control group,the differences were statistically significant,P<0.05.Conclusion The effect of tirofiban on PCI patients with acute myocardial infarction is better than that of tirofiban,which can promote coronary artery reflow more effectively.