纤维蛋白原,降钙素原,超敏C反应蛋白以及白细胞计数检测在评判儿童是否为细菌感染肺炎中的应用价值

The application value of FIB,PCT,hs-CRP and WBC in diagnosing bacterial pneumonia in children

目的:探讨血浆纤维蛋白原(Fibrinogen,FIB),血清降钙素原(Procalcitonin,PCT),超敏C反应蛋白(High Sensitivity C-reactive Protein,hs-CRP)含量以及白细胞计数(White Blood Cell Count,WBC)在临床上判断患儿是否为细菌感染肺炎的意义。方法:选取我院2018年3月-2019年9月收治的细菌感染肺炎患儿(A组)80例,非细菌感染肺炎患儿(B组)68例,体检健康儿童(C组)80例作为研究对象,检测各组儿童空腹静脉血中FIB,PCT,hs-CRP以及WBC水平的差异。进一步分析各单项指标以及四项联合指标细菌感染肺炎检出阳性率在各组之间的差异。结果:A组FIB,PCT,hs-CRP以及WBC水平均显著高于B组和C组(P<0.05),B组和C组之间无显著差异(P>0.05)。A组FIB,hs-CRP,PCT,WBC单一指标检出率以及四项指标联合检出率显著高于B组和C组(P<0.05)。结论:FIB,PCT,hs-CRP以及WBC检测能够有效鉴别小儿细菌感染肺炎,在临床上可用于对细菌感染肺炎类型的鉴别和诊断。

Objective:To investigate the clinical significance of FIB,PCT,hs-CRP and WBC in diagnosing bacterial pneumonia in children.Methods:80 children with bacterial pneumonia(Group A),68 children with non bacterial pneumonia(Group B)and 80 healthy children(Group C)were selected as the research objects.The levels of FIB,PCT,hs-CRP and WBC in groups were detected.The difference of positive rate of bacterial pneumonia among each group,single indicator and four-indicator were further analyzed.Results:The levels of FIB,PCT,hs-CRP and WBC in Group A were significantly higher than Group B and Group C(P<0.05),there was no significant difference between Group B and Group C(P>0.05).The detection rate of FIB,hs-CRP,PCT and WBC by single indicator and four-indicator in Group A were significantly higher than Group B and Group C(P<0.05).Conclusion:The detection of FIB,PCT,hs-CRP and WBC can effectively identify bacterial pneumonia in children,and can be used in the clinical identification and diagnosis of bacterial pneumonia.