针灸、艾灸联合蜡疗应用于冻融胚胎移植周期中的效果分析

Effects of acupuncture and moxibustion plus wax therapy onpatients in FET cycle

目的:分析评价针灸、艾灸联合蜡疗应用于冻融胚胎移植(Freeze-thaw Embryo Transfer,FET)周期中的临床效果。方法:选取2017年4月-2018年12月于我院生殖中心进行冻融胚胎移植治疗的患者84例,采用随机数字表法分为对照组和研究组,每组各42例。对照组于月经干净后第2天开始口服补佳乐建内膜,不进行中医三联治疗;研究组患者在解冻移植当月月经干净后即开始行中医三联疗法治疗,即针灸、艾灸、蜡疗联合治疗。治疗10天后,对比两组患者子宫内膜容受性及妊娠结局。结果:研究组患者子宫内膜厚度8~15 mm比例显著高于对照组,子宫动脉血流脉搏指数(PI)、阻力指数(RI)均显著低于对照组,差别均有统计学意义(P<0.05)。研究组患者内膜C型血流比例以及内膜穿支血管数目显著高于对照组,差别均有统计学意义(P<0.05)。研究组患者妊娠率显著高于对照组,差别均有统计学意义(P<0.05)。结论:对于行冻融胚胎移植患者,采用针灸、艾灸联合蜡疗可以显著改善患者子宫内膜容受性,增加妊娠率,值得进一步推广。

Objective:To analyze and evaluate the effect of acupuncture and moxibustion plus wax therapy on patients in FET cycle.Methods:84 patients were divided into the control group and research group by random number table method,42 cases in each.The control group was given Bujiale(补佳乐)on the second day after menstruation clean,and the study group was treated by the treatment of triple therapy of TCM(including acupuncture and moxibustion plus wax therapy)more after the menstruation cleaned.Results:The proportion of 8~15 mm endometrial thickness in the study group was significantly higher than the control group.PI and RI of uterine artery blood flow in the study group were significantly lower than the control group,with statistically significant differences(P<0.05).The proportion of endometrial C-type blood flow and the number of intimal perforating vessels in the study group were significantly higher than the control group(P<0.05).The pregnancy rate in the study group was significantly higher than the control group,with statistically significant difference(P<0.05).Conclusion:Acupuncture and moxibustion plus wax therapy on patients in FET cycle can significantly improve the endometrial receptivity,increase the pregnancy rate,and is worthy of further promotion.