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布地奈德雾化吸入联合阿奇霉素治疗小儿肺炎支原体肺炎的临床效果 被引量:19

Clinical effect of budesonide aerosol inhalation combined with azithromycin in the treatment of children with Mycoplasma pneumoniae pneumonia
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摘要 目的探讨布地奈德雾化吸入联合阿奇霉素治疗小儿肺炎支原体肺炎的临床效果。方法将120例肺炎支原体感染的小儿肺炎患儿随机分为对照组与观察组,各60例。对照组给予阿奇霉素治疗,观察组在对照组基础上给予布地奈德雾化吸入。比较两组的临床效果。结果观察组的治疗总有效率高于对照组(P<0.05)。观察组的发热、咳嗽、喘息和肺部啰音消失时间均短于对照组(P<0.05)。治疗后,两组的FEV1、FVC、PEF均升高,CRP、TNF-α水平、ESR均降低,且观察组优于对照组(P<0.05)。结论布地奈德雾化吸入联合阿奇霉素治疗小儿肺炎支原体肺炎的效果显著,可促进患儿临床症状改善,降低炎症水平,改善肺功能。 Objective To investigate the clinical effect of budesonide aerosol inhalation combined with azithromycin in the treatment of children with Mycoplasma pneumoniae pneumonia.Methods A total of 120 children with pneumonia infected by Mycoplasma pneumoniae were randomly divided into control group and observation group,with 60 cases in each group.The control group was given azithromycin treatment,and the observation group was given budesonide aerosol inhalation on the basis of the control group.The clinical effects of the two groups were compared.Results The total effective rate of treatment in the observation group was higher than that in the control group(P<0.05).The time of fever,cough,wheezing and lung rales disappearance in the observation group were shorter than those in the control group(P<0.05).After treatment,the FEV1,FVC and PEF in both groups increased,the levels of CRP,TNF-αand ESR decreased,and those in the observation group were better than the control group(P<0.05).Conclusion Budesonide aerosol inhalation combined with azithromycin in the treatment of children with Mycoplasma pneumoniae pneumonia has a significant effect,it can promote the improvement of clinical symptoms,reduce the level of inflammation,and improve lung function.
作者 唐露 崔栋 TANG Lu;CUI Dong(Xi'an XD Group Hospital,Xi'an 710077,China)
机构地区 西电集团医院
出处 《临床医学研究与实践》 2020年第26期92-94,共3页 Clinical Research and Practice
关键词 布地奈德 阿奇霉素 小儿肺炎支原体肺炎 budesonide azithromycin children with Mycoplasma pneumoniae pneumonia
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