湖北地区不同年龄、不同性别人群新型冠状病毒核酸检测结果回顾性分析

Retrospective analysis of 2019 novel coronavirus nucleic acid test results among individuals of different age and gender in Hubei Province

目的:回顾性分析湖北地区新型冠状病毒(2019 novel coronavirus,2019-nCoV)核酸检测结果在不同年龄、不同性别间的差异,为新型冠状病毒肺炎(coronavirus disease 2019,COVID-19)疫情防控提供依据。方法:选定84611名受检者为研究对象,分为0~、10~、20~、30~、40~、50~、60~、70~和80~共9个年龄段组,每个年龄段又分为男性组和女性组。将每组各个受检者的2019-nCoV核酸检测结果进行统计分析。结果:全部受检人群2019-nCoV核酸的阳性率为5.33%,以仅N基因阳性为主,占全部阳性病例的比重为66.42%。2019-nCoV核酸阳性率随着受检者年龄的增长而逐步增高,峰值出现在60~年龄段。女性2019-nCoV核酸整体阳性率(6.21%)明显高于男性(4.64%),差异有统计学意义(P<0.05),主要是20~60岁年龄段的女性2019-nCoV核酸阳性率比男性高(各年龄段组内女性与男性比较,均P<0.05)。结论:2019-nCoV核酸阳性率与年龄、性别相关,20~60岁女性比男性更易感染,70岁以前2019-nCoV核酸阳性率随受检者年龄的增长而逐步增高。

Objective:To retrospectively analyze the difference of 2019 novel coronavirus(2019-nCoV)nucleic acid test results among individuals of different age and gender in Hubei area,and provide prevention and treatment strategies of coronavirus disease 2019(COVID-19).Methods:A total of 84611 examinees were collected and divided into 9 groups by age:0-,10-,20-,30-,40-,50-,60-,70-,and 80-.Each age group was divided into male group and female group.The results of 2019-nCoV nucleic acid test in each group were statistically analyzed.Results:Positive rate of 2019-nCoV nucleic acid test was 5.33%in all examinees,among which only N gene positive results accounted for 66.42%.Positive rates of 2019-nCoV nucleic acid test were increased gradually with age,and reached the peak in 60-years old group.Positive rate of 2019-nCoV nucleic acid test in entire female group was 6.21%and significantly higher than that in entire male group(4.64%),and the differences were caused mainly by 20-60 years old female groups which had obviously higher positive rates of 2019-nCoV nucleic acid test than same age male groups(P<0.05).Conclusion:Positive rates of 2019-nCoV nucleic acid test are related to age and gender.The female aged 20-60 are more susceptible to infection than men.The positive rates of 2019-nCoV nucleic acid test were gradually increased with age before 70 years old.