预防性使用环丙沙星对输尿管软镜取石术患者术后相关感染性并发症的影响

Effect of prophylactic use of ciprofloxacin on postoperative infectious complications in patients undergoing ureteroscopic lithotomy

目的探讨预防性使用环丙沙星对输尿管软镜取石术患者术后相关感染性并发症的影响。方法选取2018年4月至2019年2月本院收治的86例行输尿管软镜取石术患者为研究对象,按照随机双盲法分为两组,各43例。对照组行输尿管软镜取石术治疗,观察组在对照组基础上术前行单次环丙沙星治疗。比较两组手术时间、术后住院时间及相关感染性并发症发生率。结果两组手术时间、术后住院时间比较差异无统计学意义;治疗后,观察组术后相关感染性并发症发生率(4.65%)显著低于对照组(20.93%),差异有统计学意义(P<0.05)。结论预防性使用环丙沙星可有效降低输尿管软镜取石术患者术后相关感染性并发症发生率,一定程度上缩短手术时间及术后住院时间,值得应用推广。

Objective To investigate the effect of prophylactic use of ciprofloxacin on postoperative infectious complications in patients undergoing ureteroscopic lithotomy.Methods From April 2018 to February 2019,86 patients with soft ureteroscopic lithotomy in our hospital were selected as the study subjects,which were divided into two groups according to the random double blind method,with 43 cases in each group.The control group was treated with ureteroscopic lithotomy,and the observation group was treated with ciprofloxacin on the basis of the control group.The operative time,postoperative hospitalization time and the incidence of related infectious complications were compared between the two groups.Results There was no significant difference in operative time and postoperative hospitalization time between the two groups.After operation,the incidence of postoperative infectious complications(4.65%)in the observation group was significantly lower than that in the control group(20.93%),and the difference was statistically significant(P<0.05).Conclusion Prophylactic use of ciprofloxacin can effectively reduce the incidence of postoperative infectious complications in patients with ureteral soft-mirror lithotomy,and shorten the operation time and postoperative hospitalization time to some extent.It is worthy of clinical promotation.