炎症性肠病相关的皮肤表现

Cutaneous manifestations associated with inflammatory bowel disease

皮肤是炎症性肠病(IBD)最常累及的肠外器官之一,其特异性和反应性皮损通常与IBD的发病机制相似。皮疹的出现往往与消化道疾病活动有关,预示着需要更加积极的治疗,包括早期使用生物制剂。本文阐述了常见的IBD皮肤表现及药物相关的皮疹及处理原则,希望能为消化科及皮肤科医生提供参考,共同强化对IBD相关皮肤病变的认识及优化治疗。

Inflammatory bowel disease(IBD)is often accompanied by extraintestinal manifestations,and the skin is one of the most commonly affected organs.The specific and reactive skin lesions usually have the similar pathogenesis as IBD.The appearance of rashes is often associated with active digestive tract diseases,indicating the requirement for more positive treatments,including the early usage of biology agents.This paper summarizes the common skin manifestations in IBD and drug-related rashes and the management principles in detail to provide a reference for both gastroenterologists and dermatologists in order to improve the understanding of the skin lesions associated with IBD and optimize the treatment.