摘要
胎龄越小的早产儿越容易受到缺血缺氧、感染及炎症等多种因素影响而导致大脑白质损伤,从而存留多种神经系统后遗症。近年来,多模态磁技术如扩散加权成像、扩散张量成像、磁共振波谱成像、磁敏感加权成像发展迅速,不仅可以对脑白质损伤的定位及定性提供大量依据,还能提供病理生理学、组织血供、细胞代谢等方面的信息。该文对多模态磁共振在早产儿脑白质损伤(white matter damage,WMD)的应用进展进行综述。
Premature infants with younger gestational age are more susceptible to a variety of risk factors,such as ischemia,hypoxia,infection and inflammatory damage.These risk factors will lead to white matter damage and cause neurological sequelae.In recent years,multimodality MRI such as diffusion weighted imaging,diffusion tensor imaging,magnetic resonance spectroscopy and susceptibility weighted imaging have developed rapidly,which provide evidence not only for the location and nature of brain damage,but also for the pathophysiology,tissue blood supply,cell metabolism.This review summarizes the application of multimodality MRI in premature infants with white matter damage.
作者
黄雪娇(综述)
富建华(审校)
Huang Xuejiao;Fu Jianhua(Department of Pediatrics,Shengjing Hospital of China Medical University,Shenyang 110004,China)
出处
《国际儿科学杂志》
2020年第8期556-560,共5页
International Journal of Pediatrics
关键词
脑白质损伤
早产儿
扩散加权成像
扩散张量成像
磁共振波谱成像
White matter damage
Premature infants
Diffusion weighted imaging
Diffusion tensor imaging
Magnetic resonance spectroscopy