78例宫颈柱状上皮异位患者宫颈分泌物标本的支原体培养及药敏试验结果分析

Analysis on Results and Drug Sensitivity of Mycoplasma Culture of Cervical Secretions in 78 Patients with Ectopic Cervical Columnar Epithelium

目的:分析宫颈柱状上皮异位患者宫颈分泌物中支原体培养及其药敏试验结果。方法:抽取2018年8月—2019年8月间医院收治的宫颈柱状上皮异位患者78例临床资料,分析其宫颈分泌物标本的支原体培养及其药敏试验结果。结果:78例宫颈柱状上皮异位患者标本中,单一解脲脲原体(Uu)感染率(74.36%)大于单一人型支原体(Mh)感染率(10.26%)和Mh+Uu感染率(15.38%)(P<0.05);Uu感染中单纯型58.82%小于颗粒型86.21%、乳突型86.67%(P<0.05);Uu对美满霉素、强力霉素敏感率分别为96.55%、98.28%,其对诺氟沙星、环丙沙星耐药率为82.76%、75.86%;Mh对美满霉素、强力霉素、阿奇霉素等敏感率均为100.00%,而其对诺氟沙星的耐药率为87.50%;Mh+Uu对强力霉素、美满霉素的敏感率均分别为94.67%、83.33%,其对壮观霉素、司帕霉素的耐药率分别为50.00%、41.67%。结论:宫颈柱状上皮异位患者宫颈分泌物中Uu感染率较高,其中病变分型为颗粒型、乳突型者更高,而对多种抗菌药物的敏感率具有一定差异,临床应根据药敏结果制定治疗方案。

Objective:To analyze the results and drug sensitivity of Mycoplasma culture of cervi-cal secretions in 78 patients with ectopic cervical columnar epithelium.Methods:Clinical data of 78 patients with ectopic cervical columnar epithelium admitted from August 2018 to August 2019 were collected to analyze the culture of Mycoplasma from their cervical secretion specimens and the results of drug sensitivity test.Results:The infection rate of single Ureaplasma urealyticum(Uu)(74.36%)was higher than that of single Mycoplasma Hominis(Mh)(10.26%)and Mh+Uu(15.38%)(P<0.05).In Uu infection,the infect rate of simple type(58.82%)was less than that of particle type(86.21%)and mastoid type(86.67%)(P<0.05).The sensitivity rates of Uu to minocycline and doxycycline were 96.55%and 98.28%,and the resistance rates of Uu to norfloxacin and ciprofloxacin were 82.76%and 75.86%,respectively.The sensitivity rate of Mh to MMC,minocycline,doxycycline and azithromycin was 100.00%,while the resistance rate to norfloxacin was 87.50%.The sensitivity rates of Mh+Uu to doxycycline and minocycline were 94.67%and 83.33%,and the drug resistance rates of Mh+Uu were 50.00%and 41.67%,respectively.Conclusion:The infection rate of Uu in the cervical secretions in patients with ectopic cervical columnar epithelium was higher,among which the lesion type is granule type and mastoid type,and the sensitivity rate to a variety of antibacterial drugs was different to some extent.Therefore,the clinical treatment plan should be formulated based on the drug sensitivity results.