针刺联合二甲双胍治疗多囊卵巢不孕症临床观察

Clinical observation of acupuncture combined with metformin in the treatment of polycystic ovarian infertility

目的:观察针刺联合二甲双胍治疗多囊卵巢不孕症临床疗效。方法:2018年8月-2019年8月收治多囊卵巢不孕症患者60例,随机分为两组,各30例。对照组给予二甲双胍治疗;试验组给予针灸联合二甲双胍治疗。比较两组治疗效果。结果:试验组持续治疗1个疗程、2个疗程、3个疗程后优势卵泡率及子宫厚度均高于对照组,差异有统计学意义(P<0.05)。试验组持续治疗3个疗程后黄体生成素、卵泡刺激素、总睾酮及雌二醇等相关激素水平均优于对照组,差异有统计学意义(P<0.05)。试验组治疗后6个月排卵率及妊娠率均高于对照组,差异有统计学意义(P<0.05)。结论:针灸联合二甲双胍治疗多囊卵巢不孕症,效果显著。

Objective:To explore the clinical effect of acupuncture combined with metformin in the treatment of polycystic ovarian infertility.Methods:From August 2018 to August 2019,60 patients with polycystic ovarian infertility were selected and randomly divided into two groups of 30 cases in each.The control group was treated with metformin.The experimental group was treated with acupuncture and metformin.We compared the efficacy of the two groups.Results:In the experimental group,after one course,two courses and three courses of continuous treatment,the dominant follicle rate and uterine thickness were higher than those in the control group,the difference was statistically significant(P<0.05).In the experimental group,after three courses of continuous treatment,the levels of luteinizing hormone,follicle stimulating hormone,total testosterone and estradiol were all better than those of the control group,the difference was statistically significant(P<0.05).In the experimental group,at 6 months after treatment,the ovulation rate and pregnancy rate were higher than those in the control group,the difference was statistically significant(P<0.05).Conclusion:The clinical effect of acupuncture combined with metformin in the treatment of polycystic ovarian infertility is significant.