老年慢性肾脏病认知衰弱相关研究进展

Research progress on cognitive frailty in elderly patients with chronic kidney disease

随着老龄化加剧,慢性肾脏病(CKD)患病率不断增高。衰弱是一种复杂的老年综合征,老年CKD患者衰弱及认知障碍的发病风险较一般老年人群高。近年来,衰弱与认知之间的关系逐渐得到国内外学者的关注。认知衰弱被视为衰弱的一种亚型,成为老年医学领域的研究热点之一。但关于老年CKD与认知衰弱的研究尚少,本文就认知衰弱的概念、流行病学、评估方法及CKD患者中可能的发病机制等方面的研究进展作一综述。

With the population aging,the prevalence of chronic kidney disease(CKD)is increasing.Frailty is a complex syndrome in the elderly.Elderly CKD patients have higher risks of frailty and cognitive im pairment than the general elderly population.In recent years,the relationship between frailty and cognition has gradually attracted the attention of researchers at home and abroad.Cognitive frailty is regarded as a subtype of frailty and has become one of the research hotspots in the field of gerontology.However,there are few studies on the relationship between CKD and cognitive frailty in the elderly.This article reviews research progress on the topic,including the epidem iology»evaluation methods and possible pathogenesis of cognitive frailty in elderly CKD patients.