显微浸润在临床靶体积定义中的研究进展

Research progress on microscopic extension in defining clinical target volume

显微浸润(亚临床病变)的范围是放疗临床靶体积定义的关键因素。本文将分别针对食管癌、肺癌、肝癌、前列腺癌、膀胱癌、直肠癌、乳腺癌、非黑色素瘤皮肤癌以及转移淋巴结的显微浸润/包膜外侵的研究结果进行综述。这些研究结果为临床靶体积的定义提供了重要的依据,但仍有许多问题值得进一步探索。

Microscopic extension(subclinical lesion)is the key factor for defining clinical target volume in radiotherapy.In this article,the research progresses on microscopic extension or extracapsular extension in esophageal cancer,lung cancer,hepatocellular carcinoma,prostate cancer,bladder cancer,rectal cancer,breast cancer,non-melanoma skin cancer and metastatic lymph nodes were reviewed.These results provide important basis for the definition of clinical target volume.However,a series of questions remain to be properly resolved.