严世芸辨治粒细胞肉瘤转化难治复发急性髓系白血病验案探析

Analysis of Yan Shiyun’s experience in treating refractory relapsed acute myeloid leukemia secondary to granulocytic sarcoma

结合案例介绍,分析严世芸教授辨治粒细胞肉瘤转化难治复发急性髓系白血病的临床经验。认为其病机为伏邪温病,临证以"扶正祛邪、圆机活法"为核心思想进行病证结合,卫气营血、八纲、脏腑辨证诸法合用,善用峻猛药、毒性药、经验药,并以牛黄醒消丸控制白血病细胞的增殖。

Combined with the introduction of a case,the clinical experience of Professor Yan Shiyun in differential treatment of refractory relapsed acute myeloid leukemia secondary to granulocytic sarcoma is analyzed.It is considered that its pathogenesis is a febrile disease caused by latent pathogenic factors.And with syndrome differentiation of Weiqi Yingxue,Bagang and Zang-fu organs,the disease is treated with the method of combining disease and syndrome differentiation guided by the core idea of"strengthening healthy qi to eliminate pathogenic factors with flexible methods through fully grasping the pathogenesis".Professor Yan Shiyun is adept at using empirical medicines and drugs with drastic or toxic actions,and prescribes Niuhuang Xingxiao pill to control the proliferation of leukemic cells.