没食子酸调控人宫颈癌HeLa细胞凋亡机制研究进展

Advances in the mechanism of gallic acid regulating apoptosis in human cervical cancer HeLa cells

概述近年来没食子酸对人宫颈癌HeLa细胞凋亡机制的研究进展。没食子酸主要是通过调控P53信号通路、调节Caspase-3水平变化、促进ROS水平升高及调控ADAM17、EGFR、AKT/p-AKT和ERK/p-erk信号通路,实现对宫颈癌HeLa细胞凋亡的调控。

To review the research progress of gallic acid on the mechanism of apoptosis of human cervical cancer HeLa cells in recent years.Gallic acid regulates the apoptosis of cervical cancer HeLa cells by regulating P53 signal pathway,regulating the change of Caspase-3 level,promoting the increase of ROS level and regulating ADAM17,EGFR,AKT/p-AKT and ERK/p-erk signal pathway.