含吡唑杂环的氨基脲Schiff碱的合成与表征

Synthesis and Characterization of Arylpyrazole Semicarbazide Schiff Base

以苯肼或取代苯肼和胺基脲为原料,通过缩合成环、Vilsmeier反应与缩合反应合成了十种芳基吡唑缩胺基脲Schiff碱,并使用FT-IR、1 H NMR、ESI-MS和元素分析对其结构进行了表征.对此类芳基吡唑缩胺基脲Schiff碱化合物的光谱性能的研究发现,目标化合物在280~300nm处有较强的紫外吸收,而其荧光光谱有两个分别位于330和350nm处的发射峰.此类Schiff碱化合物合成方法简单,分离纯化容易,收率较好.

Ten arylpyrazole semicarbazide Schiff bases were synthesized through exocondensation,Vilsmeier reaction and condensation reaction from phenylhydrazine or substituted phenylhydrazine and amino urea in good yields.Their structures were characterized by FT-IR,1 H NMR and ESI-MS.The studies of the spectral properties of the arylpyrazole semicarbazide Schiff base compounds showed that the target compounds had strong UV-vis absorption at 280-300nm,and the fluorescence spectra have two emission peaks at 330and 350nm,respectively.The synthesis of these Schiff base compounds is simple,the separation and purification is easy,and the yield is good.