认知行为疗法联合佐匹克隆治疗慢性失眠症的临床研究

Clinical Research of Cognitive Behavior Therapycombined with Zopiclone in Treatment of Chronic Insomnia

目的探讨认知行为疗法联合佐匹克隆治疗慢性失眠症的效果。方法选取慢性失眠症患者80例,按随机数字表法1:1分为观察组和对照组,每组40例。对照组给予佐匹克隆治疗,观察组在此基础上给予认知行为疗法治疗。观察两组治疗前与治疗后匹茨堡睡眠质量指数量表(PSQI)得分和总体幸福感量表(GWB)得分的变化,评价临床疗效。结果观察组临床疗效显效率显著高于对照组,差异有统计学意义(P<0.05)。治疗前,两组PSQI得分和GWB得分比较差异无统计学意义(P>0.05);治疗后,观察组PSQI得分显著低于对照组,观察组GWB得分显著高于对照组,差异具有统计学意义(P<0.05)。结论与单纯佐匹克隆治疗相比,在此基础上联用认知行为疗法可有效增进临床疗效,改善慢性失眠症患者的睡眠质量,提高慢性失眠症患者的总体幸福感。

Objective Effect of cognitive behavior therapycombined with zopiclone in treatment of chronic insomnia.Methods80 patients chronic insomnia were selected from January 2018 to June 2019 in our hospitals,and were according to the random indicator method divided into Observation group and Control group,40 cases in each group.Control group received Cognitive behavior therapy,and Zopiclone was added in the Observation group.Changes in the Pittsburgh sleep quality index(PSQI)and General wellbeing schedule(GWB)in two groups were observed before treatment and after treatment,also the efficacy in each groups was assessed.Results The total marked improvement rateof Observation group was higher than Control group,tatistically significant(P<0.05).Before treatment,score of PSQI and GWB,the difference between the tow groups was not significant(P>0.05).After treatment,score of PSQIin the Observation group was lower than Control group,score of GWB in Observation group was higher than Control group,tatistically significant(P<0.05).Conclusion Compared with the simple zopiclone treatment,the combination of cognitive behavior therapy on this basis can effectively improve the clinical efficacy,improve the sleep quality of chronic insomnia patients,improve the overall well-being of chronic insomnia patients.