放射性脑损伤机制与防治方法研究进展

Review on the mechanism,prevention and treatments of radiation brain injury

原发性或转移性脑部恶性肿瘤患者接受放射治疗时,会引起脑组织功能和形态学变化,导致放射性脑损伤,患者表现出一系列并发症甚至死亡。本文就近年来研究者提出的针对放射性脑损伤发病机制与防治方法做一综述,为临床预防和治疗提供理论基础。

When patients with primary or metastatic brain malignant tumor receive radiotherapy, it usually causes changes to brain tissue function and morphology, leading to radiation brain injury. As a result, patients show a series of complications and that even lead to deaths. In this paper, we reviewed the mechanisms of radiation brain injury, its prevention and treatment strategies proposed in recent years, hoping to provide theoretical basis for clinical treatment.