拟南芥TIR3基因的功能研究进展

Advances in the research of Arabidopsis TIR3 gene function

拟南芥TIR3(transport inhibitor response3)基因通过调控生长素的极性运输广泛参与器官的形态建成。TIR3基因的缺失会导致生长素极性运输和浓度分布发生改变,致使植物花、叶、根等器官出现明显的发育缺陷。此外,TIR3可作为一种新的调节因子参与植物免疫防御机制和生理节律的调控。本文综述了TIR3通过调控NBP(NPA binding protein)及PIN1(PIN-FORMED1)蛋白进而影响植物对生长素响应的机制,及其参与植物花、叶、根等器官形态建成的分子机制。简述了TIR3通过调控生长素的运输进而引起茉莉酸(JA)响应变化、JA和乙烯(ET)的协同作用以及其他激素的相互作用,从而参与植物免疫应答过程。简述了TIR3等位基因可能参与调控植物生理节律的相关研究。展望了TIR3未来的研究方向、发展趋势及对农业生产的借鉴意义。

Arabidopsis TIR3(transport inhibitor response3)gene is widely involved in organ morphogenesis by regulating the polar auxin transport.The mutation of TIR3 gene can affect the polar auxin transport and concentration distribution,which lead to obvious developmental defects in flowers,leaves and roots.In addition,TIR3 can act as a new regulator to participate in the regulation of plant defense and circadian rhythm.This article reviewed the molecular function of TIR3 in auxin response by regulating the location and distribution of NPA binding protein(NBP)and PIN1(PIN-FORMED1)protein,and its role in plant organogenesis such as flowers,leaves and root.The role of TIR3 in plant immune response by regulating auxin transport to induce JA response,JA and ET cross reaction,and crosstalk with other plant hormones were also reviewed.Recent advances in the function of TIR3 alleles in affecting plant circadian rhythm were summarized.Future research perspective of the molecular mechanism of TIR3 gene and its potential applications in agriculture were discussed.