人工真皮在治疗特重度烧伤后期功能重建中的临床效果分析

Analysis of the clinical effect of artificial dermis in the treatment of functional reconstruction after severe burn

目的:针对特重度烧伤患者,研究人工真皮对其后期功能重建的临床效果。方法:收集2018年1月至2018年12月在本院治疗的特重度烧伤患者40例,按照数字法随机分成观察组和参照组。观察组采取人工真皮治疗,行厚皮植皮术;参照组采取中厚皮片移植术。对比两组瘢痕改善情况、皮片成活率、创面感染例数和创面愈合时间。结果:术后6个月,观察组VSS评分(7.18±1.52)分低于参照组的(9.02±1.43)分,术后12个月,观察组VSS评分(2.86±1.35)分低于参照组的(4.57±2.06)分;观察组皮片成活率(90.00%)高于参照组(60.00%),观察组创面感染率(5.00%)低于参照组(30.00%),观察组创面愈合时间(23.54±6.19)d短于参照组的(34.26±6.53)d。两组差异有统计学意义(P<0.05)。结论:针对特重度烧伤患者,采用人工真皮治疗,具有较高的皮片成活率,感染风险低,促进了创面的愈合,同时有效改善了瘢痕,对后期皮肤功能重建具有积极的作用。

Objective:To study the clinical effect of artificial dermis on functional reconstruction in patients with severe burn.Methods:40 patients with severe burn treated in our hospital from January 2018 to December 2018 were collected and randomly divided into the experimental group and the reference group according to the numerical method.The experimental group was treated with artificial dermis and treated with thick skin graft.The reference group underwent medium thickness skin grafting.The improvement of scar,skin survival rate,number of cases of wound infection and wound healing time were compared between the two groups.Results:VSS score of the experimental group(7.18±1.52)was lower than that of the control group(9.02±1.43)6 months after surgery,and that of the experimental group(2.86±1.35)was lower than that of the control group(4.57±2.06)12 months after surgery.The skin survival rate of the experimental group(90.00%)was higher than that of the control group(60.00),the wound infection rate of the experimental group(5.00%)was lower than that of the control group(30.00%),and the wound healing time of the experimental group(23.54±6.19)was shorter than that of the control group(34.26±6.53).The difference between the two groups was statistically significant(P<0.05).Conclusion:For the patients with extremely severe burns,artificial dermis treatment has a high skin slice survival rate,low risk of infection,promotes wound healing,and effectively improves scar formation,which has a positive effect on the later skin functional reconstruction.