人体感染东方毛圆线虫的发现与诊治

Diagnosis and treatment of human infection of Trichostrongylus orientalis

目的观察疑似感染东方毛圆线虫病例进行病原学诊断与治疗效果。方法收集住院患者临床资料,包括病史、临床特征、实验室检查、流行病学史等进行分析。粪便样本显微镜多次镜检东方毛圆线虫卵。结果患者,女,65岁,籍贯安徽,5年前移居厦门。因劳累后出现背部皮肤突起成簇带状水疱,伴明显疼痛,就诊于当地诊所,予以“伐昔洛韦”等药物治疗后疼痛无明显缓解,且水疱逐渐增多,并延及腰部,部分水疱形成糜烂。于2018年11月7日,入住厦门市第一医院。经实验室血常规、血液生化与专科检查,排除单纯疱疹及其它疾病。粪便检查,发现拟似钩虫卵,送福建省疾病预防控制中心检测鉴定为东方毛圆线虫卵。最后诊断为东方毛圆线虫感染致病,合并“带状疱疹”,按常规驱虫与抗病毒治疗后痊愈出院。结论东方毛圆线虫是一种罕见或少见的人体寄生虫,加强监测与防控工作,以减少人体感染致病的危险。

We observed an case of suspected Trichostrongylus orientalis by phthogenicity tools(microscopic detection of insect eggs),as well as the diagnosis and treatment.Clinical information of the patient was collected.the fecal samples were examined by microscopy for multiple detection eggs.The patient was a 65-year-old female from Anhui Province.She was shown in ganglionitisherpes on backside by tiredly with obvious pain(October 19,2018).The symptoms were not relieved after treatment with heteropathy in the local hospital.The patient was then transferred to the first hospital of Xia-men University(November 7,2018).On November 14,the fecal samples of the patient were sent to Fujian Provincial Center for Disease Control and Prevention for T.orientalis examination.T.orientalis eggs were found in the stool-mass samples by microscopy.The case is confirmed to be T.orientalis infection by phthogenicity tools.Therefore,the prevention and control measures should be focused on survey,so as to reduce the risk of human infection.