绒毛膜羊膜炎研究现状

Present Situation of Chorioamnionitis

绒毛膜羊膜炎是一个长期困扰母胎医学和新生儿学的问题,大多数是由于感染引起的。病理学的检查是诊断它的金标准。但同时,临床、生化和微生物检查的各项指标也被用来定义该疾病。文献中有大量证据表明,绒毛膜羊膜炎是早产的主要原因,因此对新生儿发病率和死亡率有显著影响。由于其病理诊断的滞后性,尤其是亚临床绒毛膜羊膜炎常常被忽略。对绒毛膜羊膜炎的早期预测、早诊断、早治疗显得尤为重要。本文对绒毛膜羊膜炎的发病机制尚及生物学指标等进行综述。以期随着绒毛膜羊膜炎的进展,使绒毛膜羊膜炎得到精准的诊断与治疗。

Chorioamnionitis is a chronic problem in maternal-fetal medicine and neonatology,mostly due to infection.The examination of the pathology is the gold standard for its diagnosis.But at the same time,clinical,biochemical and microbiologi cal indicators are also used to define the disease.There is abundant evidence in the literature that chorionic amnionitis is the main cause of premature birth and therefore has a significant impact on neonatal morbidity and mortality.Subclinical chorioamnionitis is often neglected because of its hysteresis in pathological diagnosis.Early prediction,early diagnosis and early treatment of chorion ic amnionitis are particularly important.This article reviews the pathogenesis and biological indexes of chorioamnionitis.With the development of chorionic amnionitis,accurate diagnosis and treatment of chorionic amnionitis can be achieved.