降钙素原检测在婴幼儿便血性腹泻中的临床价值研究

Study on the clinical value of procalcitonin detection in infants and young children with hemorrhagic diarrhea

目的探讨婴幼儿便血性腹泻采用降钙素原(PCT)检测的临床价值。方法选取2017年11月~2018年11月在本院检测的76例便血性腹泻患儿,将其按照不同病原体行有效分组,分为细菌性腹泻组(n=24)、病毒性腹泻组(n=25)及非感染性腹泻组(n=27),检测三组患儿的PCT及C反应蛋白(CRP)水平,并比较实验室阳性检查率。结果采用PCT及CRP水平检测三组患者情况可知,细菌性腹泻组患者PCT及CRP水平较病毒性腹泻组、非感染性腹泻组显著提升,组间存在显著差异(P<0.05),病毒性腹泻组、非感染性腹泻组PCT、CRP水平无显著差异(P>0.05);细菌性腹泻组采用PCT水平检测,阳性检出率为83.33%,采用CRP水平检测,检出率为79.17%,检出率显著高于病毒性腹泻组、非感染性腹泻组,组间有显著差异(P<0.05),病毒性腹泻组、非感染性腹泻组采用PCT及CRP水平阳性检出率无显著差异(P>0.05)。结论婴幼儿便血性腹泻检测中采用PCT及CRP水平进行检测,可显著提升细菌性感染腹泻阳性检出率,PCT及CRP水平均可作为小儿腹泻诊断中的重要指标。

Objective To explore the clinical value of procalcitonin(PCT)detection in infants and young children with hemorrhagic diarrhea.Methods 76 children with hemorrhagic diarrhea detected in our hospital from November 2017 to November 2018 were selected and grouped according to different pathogens.They were divided into bacterial diarrhea group(n=24),viral diarrhea group(n=25)and non-infectious diarrhea group(n=27).The PCT and C-reactive protein(CRP)levels of the three groups were detected,and the laboratory positive rate was compared.Results PCT and CRP levels detection of the three groups showed that the PCT and CRP levels of the bacterial diarrhea group were significantly higher than those of the viral diarrhea group and the non-infectious diarrhea group,with significant differences between the groups(P<0.05).There was no significant difference in PCT and CRP levels between viral diarrhea group and non-infectious diarrhea group(P>0.05).The positive rate of PCT and CRP level detection in bacterial diarrhea group was 83.33%and 79.17%respectively.The positive rate in bacterial diarrhea group was significantly higher than that in the viral diarrhea group and non-infectious diarrhea group(P<0.05).There was no significant difference in the positive detection rate of PCT and CRP in the viral diarrhea group and non-infectious diarrhea group(P>0.05).Conclusion The detection of PCT and CRP levels in hemorrhagic diarrhea in infants and young children can significantly increase the positive detection rate of bacterial infection diarrhea.Both PCT and CRP levels can be used as important indicators in the diagnosis of diarrhea in young children.