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百令胶囊联合前列地尔治疗糖尿病肾病患者的临床价值分析 被引量:1

Clinical value of Bailing capsule combined with alprostadil in the treatment of diabetic nephropathy
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摘要 目的探讨百令胶囊联合前列地尔治疗糖尿病肾病患者的临床价值。方法随机选取2018年5月至2019年5月本院收治的80例糖尿病肾病患者,随机分为常规组(n=40)与实验组(n=40)。常规组患者给予前列地尔治疗,实验组患者在常规组的基础上配合百令胶囊治疗。比较两组患者的疗效、尿蛋白水平和不良反应发生情况。结果实验组患者治疗总有效率为95.00%,高于常规组的80.00%,差异有统计学意义(P<0.05);治疗后,实验组24 h尿蛋白定量和24 h尿微量蛋白的水平均明显低于常规组,差异有统计学意义(P<0.05);两组患者不良反应发生率比较差异无统计学意义。结论百令胶囊联合前列地尔治疗糖尿病肾病疗效显著,可有效改善患者尿蛋白水平,且不会增加不良反应,安全性较高,可在临床推广。 Objective To explore the clinical value of Bailing capsule combined with alprostadil in the treatment of diabetic nephropathy.Methods 80 patients with diabetic nephropathy from May 2018 to May 2019 treated in our hospital were randomly selected and they were divided into routine group(n=40)and experimental group(n=40).The routine group was treated with alprostadil,while the experimental group was treated with Bailing capsule on the basis of the routine group.The curative effect,urinary protein level and adverse reactions were compared between two groups.Results The total effective rate was 95.00%in the experimental group,which was higher than that(80.00%)in the routine group,and the difference was statistically significant(P<0.05).After treatment,the levels of 24-hour urinary protein and 24-hour urinary microprotein in the experimental group were significantly lower than those in the routine group,and the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups.Conclusion Bailing capsule combined with alprostadil in the treatment of diabetic nephropathy has a high efficacy,can effectively improve the level of urinary protein,and will not increase adverse reactions,high safety,can be promoted in clinical practice.
作者 刘晶 刘娇 Liu Jing;Liu Jiao(Department of Fifth Internal Medicine,The Second People's Hospital of Yichun,Yichun,Jiangxi,336000,China)
出处 《当代医学》 2020年第29期76-78,共3页 Contemporary Medicine
关键词 百令胶囊 前列地尔 糖尿病肾病 治疗价值 Bailing capsule Alprostadil Diabetic nephropathy Therapeutic value
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  • 1窦敬芳,翁孝刚.百令胶囊防治糖尿病肾病的临床研究[J].时珍国医国药,2006,17(6). 被引量:11
  • 2UK Prospective Diabetes Study Group. Tight blood pressurecontrol and risk of macrovascular and microvascular complicationsin type 2 diabetes: UKPDS 38. BMJ, 1998,317 : 703-713.
  • 3Moln6r M, Wittmann i, Nagy J. Prevalence, course and risk factors of dia- betic nephropathy in type-2 diabetes mellitus. Med Sci Monit, 2000,6 : 929-936.
  • 4Islam N, Kazmi F, Chuney GD, et al. Ethnic differences in correlates of microabluminuria in NIDDM the role of the acutephase response. Diabetes Care,1998,3 : 385.
  • 5Diamond JR. Analogous pathobialogic mechanism in glomerulosclerosis and atherosclerosis. Kidney Intl,1991,39: $29-$34.
  • 6Nelson RG, Knowler WC, Pettit D J, et al. Incidence and determinants of elevated urinary albumin excretion in Pima Indiants with NIDDM. Diabe- tes Care,1995,18 : 182-187.
  • 7Gall MA, Hougaad P, Borch-Johnsen K, et al. Risk factors fordevelopment of incipient and overt diabetic nephropathy in patients with non-insulin dependent diabetic mellitus : prospective, observational study. BMJ, 1997, 314 :.783-778.
  • 8Ravid M, Brosh D, Ravid-Safran D, et al. Main rislt factors for nephropa- thy in type 2 diabetes mellitus are plasma cholesterol levels, mean blood pressure, and hyperglycemia. Arch Intern Med, 1998,158:998-1004.
  • 9Bamilay JI, Abraham L, Heekbea SR, et al. The relation of inflammation to the development of glucose disorders in the elderly : the cardiovascu- lar health study. Diabetes ,2011,50 : 2348-2389.
  • 10苏宏业,王乃尊.糖尿病肾病治疗研究[J].医学综述,2008,14(9):1376-1378. 被引量:51

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