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富血小板血浆治疗椎间盘退变的研究进展 被引量:3

Progress in the treatment of intervertebral disc degeneration with platelet-rich plasma
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摘要 2015年的一项统计发现,全球范围内超过5.4亿人患有不同程度的腰痛(low back pain,LBP),该病引起的疼痛和功能丧失,给社会经济以及家庭带来了巨大负担,严重降低了患者的生活质量,已成为致残的首要病因[1]。LBP常由椎间盘退变(intervertebral disc disease,IDD)引起,特点是髓核脱水、纤维环撕裂、软骨终板裂隙、炎症因子释放等,具体的分子机制还有待进一步的研究[2]。
作者 孙阳 李小飞 马胜山 金成哲 王黎明 谢文瑾 SUN Yang;LI Xiaofei;MA Shengshan
出处 《中国脊柱脊髓杂志》 CAS CSCD 北大核心 2020年第8期762-766,共5页 Chinese Journal of Spine and Spinal Cord
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  • 2Kepler CK. Anderson DG. Tannoury C. et al. Intervertebral disk degeneration and emerging biologic treatments[J]. J Am Acad Orthop Surg .2011 .19(9) :543 - 553.
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  • 8Masuda K. Aota Y. Muehleman C. et al. A novel rabbit model of mild. reproducible disc degeneration by an anulus needle puncture: correlation between the degree of disc injury and radiological and histological appearances of disc degeneration[J]. Spine (Phila Pa 1976).2005.30 (1) : 5 - 14.
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