磁共振检查联合外周血人白细胞抗原B27对强直性脊柱炎患者髋关节病变的评估价值

Value of magnetic resonance imaging combined with peripheral blood human leukocyte antigen B27 detection in evaluating hip joint lesions in ankylosing spondylitis patients

目的探究磁共振检查联合外周血人白细胞抗原B27(HLA-B27)对强直性脊柱炎(ankylosing spondylitis,AS)患者髋关节病变的评估价值。材料与方法选取2017年2月至2019年2月我院收治并确诊为AS髋关节病变患者186例为研究对象,所有患者行MRI检查,并检测外周血HLA-B27,通过比较不同检查方式的准确性,评估其对AS髋关节病变患者的诊断价值。结果外周血HLA-B27阳性152例,阴性34例,阳性率81.72%;MRI检查结果显示,186例AS患者中有280个(83.33%)髋关节受累,其中210个(75.00%)髋关节囊积液,181个(64.64%)髋关节骨髓水肿,其他AS髋关节病变类型占比低于60%;MRI+HLA-B27法检出率(96.43%)显著高于MRI检出率(83.33%),差异具有统计学意义(P<0.05)。结论MRI检查联合外周血HLA-B27检测能有效提高AS髋关节病变患者诊断准确率,对临床治疗具有良好的评估价值。

Objective:To investigate the value of magnetic resonance imaging combined with peripheral blood human leukocyte antigen B27(HLA-B27)detection in evaluating hip joint lesions in ankylosing spondylitis(AS)patients.Materials and Methods:One hundred and eighty-six AS patients with hip joint lesions treated in our hospital from February 2017 to February 2019 were enrolled,all patients received the magnetic resonance imaging and HLA-B27 detection.The accuracy of different examinations was compared,and the diagnostic value of the two methods for AS patients with hip joint disease was also analyzed.Results:The examination showed that 152 cases of HLA-B27 were positive in peripheral blood and 34 cases were negative,with a positive rate of 81.72%;The results of MRI showed that 280 hips(83.33%)were involved in 186 AS patients,210 hips(75.00%)had hydrocele and 181 hips(64.64%)had bone marrow edema.Other types of AS hip joint lesions accounted for less than 60%.The detection rate of MRI+HLA-B27 examination was significantly higher than that of MRI examination(96.43% vs 83.33%,P<0.05).Conclusions:MRI combined with peripheral blood HLA-B27 detection can effectively improve the diagnostic accuracy of AS patients with hip joint disease.