视神经脊髓炎认知功能障碍的多模态MRI研究进展

Advances in multimodal MRI of cognitive impairment in neuromyelitis optica

视神经脊髓炎是一种中枢神经系统炎性脱髓鞘疾病,除视神经和脊髓受累外,还可累及大脑半球,导致认知功能障碍。近年来,诸多国内外学者对视神经脊髓炎认知功能障碍进行了临床和影像学研究。多模态MRI从影像学角度为阐述其认知损害发生的可能机制提供了重要依据。笔者对近年来视神经脊髓炎认知功能障碍的MRI研究进展作简要综述。

Neuromyelitis optica(NMO)is an inflammatory demyelinating disease of central nervous system(CNS)whose main characteristic is the compromise of the spinal cord and the optic nerves.Moreover,it can also affect the brain,leading to cognitive impairment.In recent years,many scholars have carried out clinical and neuroimaging studies on cognitive impairment of neuromyelitis optica.And multimodal MRI plays an important role in explaining the possible mechanism behind it.The purpose of this article is to review the recent MRI findings in cognitive impairment in NMO.