创伤性脊髓损伤的MRI评价方法

Applications of magnetic resonance imaging in traumatic spinal cord injury

创伤性脊髓损伤(traumatic spinal cord injury,TSCI)是最常见的创伤性中枢神经损伤之一,发病率、致残率、致死率较高。脊髓损伤的病理生理机制复杂,临床治疗效果不佳,给家庭和社会带来了沉重负担。当常规T2WI发现脊髓异常信号时,提示损伤严重不可逆。目前,由传统的MRI技术发展出的纤维束成像等无创性功能成像技术,不仅可以观察脊髓的形态和信号改变,还可以进行脊髓微观结构的研究,诊断优势在于多模态、精确、无创。现就无创性MRI技术在创伤性脊髓损伤方面的进展进行综述,旨在为临床医生早期诊断脊髓损伤以及制定正确的治疗方案提供重要参考。

Traumatic spinal cord injury(SCI)is one of the most common traumatic central nervous system injuries,with high disability and mortality rate.With the development of transportation and construction industry,the incidence of SCI is increasing year by year.The pathophysiological mechanism of SCI is complex,and the clinical treatment effect is unsatisfied,which brings heavy burden to the family and society.When the T2WI signal is found abnormal,the injury will be severely irreversible.At present,non-invasive MRI technology can not only observe the morphology and signal changes of the spinal cord,but also study the microstructure of it.MRI is a multi-modality method to diagnose traumatic SCI,it’s also a non-invasive and accurate way.Here,the progress of non-invasive MRI technology in traumatic SCI is reviewed in terms of providing a significant clinical reference for diagnosis and treatment.